PercAssist eVAD™ System

Extravascular Ventricular Assist Device

Developing the next-generation direct cardiac compression technology for mechanical circulatory support (MCS)

UNMET NEED

VADs provide mechanical circulatory support when the heart is unable to pump sufficient blood throughout the body

ACUTE

DURATION OF DEVICE USE

CHRONIC

DAYS/WEEKS

Acute Treatment

Cardiogenic Shock Patients

~150,000

per year / United States

WEEKS/MONTHS

Mid to Long-Term Treatment

End Stage Heart Failure Patients

~200,000

per year / United States

MONTHS/YEARS

Long-Term Treatment

Heart Failure Patients

>6MM

per year / United States

Significant risks and complications exist with the current intravascular standard of care

Major bleeding

Sepsis & infection

Renal failure

Vascular injury

Hemolysis

Limb ischemia or stroke

OUR SOLUTION

PercAssist eVAD™ System for Temporary Mechanical Circulatory Support

Novel extravascular, intrapericardial system designed to provide direct cardiac compression and biventricular augmentation

No vascular access

No adjunctive anti-coagulants

Pulsatile

Synchronized inflation with patient’s natural heart rhythm
No motorized impeller

PercAssist eVAD™ System Placement

PercAssist eVAD™ System Intrapericardial Positioning

COMPANY PROGRESS

Preclinical Program

Acute, chronic, and pressure-volume (PV) loop preclinical studies have been completed

Results support safety and biventricular hemodynamic performance

Publications with the results are forthcoming

Clinical Program

First-in-Human study of the PercAssist eVAD™ System in Europe (complete)

Multisite expansion to assess safety, feasibility, and hemodynamic performance in patients with cardiogenic shock (in process)

Early Feasibility Study in South America (coming soon)

Intellectual Property

Patents have been issued for the PercAssist eVAD™ System:

United States

European Union

Japan

Australia

China

South Korea

OUR TEAM

Experienced Leadership Team

Gerardo Noriega

President & Chief Executive Officer
Albert Chin, MD

Chief Innovation & Product Development Officer
Susan Osborne

VP Regulatory, Clinical & Quality
Mladenka Dominikovic

VP of Operations
Melissa Schweizer

Manager Research & Development
Ann Benham

Head of Marketing Operations

World-Renowned Clinical Advisory Board

Daniel Burkhoff, MD, Ph.D

Director of Heart Failure,
Hemodynamics & MCS Cardiovascular
Research Foundation
Prof. Petr Neužil, MD

Chairman, Dept of Cardiology, Na Homolce Hospital, Prague, CZ
Mitchell Krucoff, MD

Director, Cardiovascular Devices Unit, Duke University Medical Center
Kendrick Shunk, MD

Chief Interventional Cardiology UCSF/SFVA
Dan Meyer, MD

Chief of Cardiac Transplantation,
Baylor Scott & White Hospital Dallas
Henry Hsia, MD

Chief of VT and Electrophysiology at UCSF,
Professor of Medicine